The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer

PHASE2RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

July 29, 2019

Primary Completion Date

November 1, 2035

Study Completion Date

November 1, 2035

Conditions
Thyroid Cancer
Interventions
DRUG

Thyrogen

intramuscular injection administered once/day for 2 consecutive days at Week 3; then once annually for subjects who meet criteria.

RADIATION

I-131

therapeutic dose administered orally to treat thyroid cancer at Week 8. 5-7 days later, the post-treatment I-131 Whole Body scan w/ SPECT is performed; then administered once annually, if the patient needs to be re-treated

RADIATION

I-124

one capsule ingested orally once at Week 3, and Week 8; then administered once annually to subjects who meet criteria.

OTHER

Thyroid hormone withdrawal

withdrawal of thyroid hormone during weeks 4 through 8

Trial Locations (1)

20892

RECRUITING

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
lead

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH