Transcranial Direct Current Stimulation for Post-stroke Motor Recovery

PHASE2CompletedINTERVENTIONAL
Enrollment

129

Participants

Timeline

Start Date

September 1, 2019

Primary Completion Date

September 19, 2024

Study Completion Date

September 19, 2024

Conditions
Stroke, IschemicMotor ActivityUpper Extremity Paralysis
Interventions
DEVICE

Sham

Sham group only receives 30 seconds of stimulation at 2mA in the beginning to create a sensory perception to the scalp in order to blind the subject.

DEVICE

Low dose tDCS

The low dose tDCS group receives direct current stimulation at 2 mA for 30 minutes per session

DEVICE

High dose tDCS

The high dose tDCS group receives direct current stimulation at 4 mA for 30 minutes per session

BEHAVIORAL

mCIMT

All three tDCS groups receive constraint-induced movement therapy as the adjunctive behavioral therapy for 2 hours per session

Trial Locations (14)

10605

Burke Rehabilitation Center, White Plains

15213

University of Pittsburgh Medical Center Presbyterian Hospital, Pittsburgh

19027

Moss Rehabilitation Research Institute, Elkins Park

20010

MedStar National Rehabilitation Hospital, Washington D.C.

27710

Duke University Hospital, Durham

29425

Medical University of South Carolina University Hospital, Charleston

30322

Emory Rehabilitation Hospital, Atlanta

35249

University of Alabama at Birmingham Hospital, Birmingham

40504

Cardinal Hill Rehabilitation Hospital, Lexington

44106

Cleveland VA Medical Center, Cleveland

45219

University of Cincinnati Medical Center, Cincinnati

77030

Memorial Hermann Texas Medical Center, Houston

90089

Keck Hospital of USC, Los Angeles

01199

Baystate Medical Center, Springfield

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

lead

Duke University

OTHER