Combination of Targeted and Immunotherapy for Advanced Biliary Tract and Esophagogastric Gastric Cancer

PHASE2WithdrawnINTERVENTIONAL
0
Timeline

Start Date

December 31, 2019

Primary Completion Date

April 30, 2021

Study Completion Date

April 30, 2022

Conditions
Esophageal CancerBiliary Tract CancerGastroEsophageal CancerHepatobiliary Neoplasm
Interventions
DRUG

DKN-01

Patient will receive DKN-01 300 mg IV every 2 weeks

DRUG

Atezolizumab

Patient will receive Atezolizumab 840 mg IV every 2 weeks until PD

DRUG

Paclitaxel

Patient will receive Paclitaxel 80 mg/m2 IV on day 1, 8 and 15 of a 28 day cycle until PD

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Hoffmann-La Roche

INDUSTRY

collaborator

Leap Therapeutics, Inc.

INDUSTRY

lead

European Organisation for Research and Treatment of Cancer - EORTC

NETWORK

NCT03818997 - Combination of Targeted and Immunotherapy for Advanced Biliary Tract and Esophagogastric Gastric Cancer | Biotech Hunter | Biotech Hunter