A SAD/MAD to Assess the Safety, PK/PD of FT-4202 in Healthy Volunteers and Sickle Cell Disease Patients

PHASE1CompletedINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

December 11, 2018

Primary Completion Date

December 17, 2021

Study Completion Date

December 17, 2021

Conditions
Healthy VolunteersSickle Cell Disease
Interventions
DRUG

FT-4202/Placebo

Participants will receive FT-4202/placebo and monitored for side effects while undergoing pharmacokinetics and pharmacodynamic studies

Trial Locations (18)

10032

Columbia University Medical Center (SCD subjects only), New York

21201

University of Maryland, Greenebaum Comprehensive Cancer Center (SCD subjects only), Baltimore

27710

Duke University Medical Center (SCD subjects only), Durham

28204

Levine Cancer Institute (SCD subjects only), Charlotte

30342

Children's Healthcare of Atlanta (SCD subjects only), Atlanta

30912

Augusta University Medical Center (SCD subjects only), Augusta

33147

Advanced Pharma CR, LLC (SCD subjects only), Miami

38105

St. Jude Children's Research Hospital (SCD subjects only), Memphis

45219

University of Cincinnati Medical Center (SCD subjects only), Cincinnati

45227

Medpace Clinical Pharmacology Unit (Healthy Volunteers only), Cincinnati

45229

Cincinnati Children's Hospital Medical Center (SCD subjects only), Cincinnati

60612

University of Illinois at Chicago (SCD subjects only), Chicago

72211

Woodland International Research Group (SCD subjects only), Little Rock

74135

Lynn Institute of Tulsa (SCD subjects only), Tulsa

77030

The University of Texas Health Science Center at Houston (SCD subjects only), Houston

90806

Collaborative Neuroscience Research, LLC (SCD subjects only), Long Beach

94607

Pacific Research Partners (SCD subjects only), Oakland

94609

UCSF Benioff Children's Hospital Oakland (SCD subjects only), Oakland

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Medpace, Inc.

INDUSTRY

lead

Forma Therapeutics, Inc.

INDUSTRY