RPTR-147 in Patients With Selected Solid Tumors and Lymphomas

PHASE1TerminatedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

October 24, 2018

Primary Completion Date

September 7, 2022

Study Completion Date

October 11, 2022

Conditions
Solid TumorLymphoma
Interventions
BIOLOGICAL

Arm A: RPTR-147:1

Escalating doses of RPTR-147:1 as a monotherapy

BIOLOGICAL

Arm B: RPTR-147:1 and Pembrolizumab

Escalating doses of RPTR-147:1 in combination with Pembrolizumab

BIOLOGICAL

Arm C: RPTR-147:2

Escalating doses of RPTR-147:2 in patients with HPV positive tumors

Trial Locations (7)

28078

Carolina BioOncology Institute, Huntersville

37203

Sarah Cannon Research Institute, Nashville

48201

Karmanos Cancer Institute, Detroit

77030

MD Anderson Cancer Center, Houston

91010

City of Hope, Duarte

06511

Yale Cancer Center, New Haven

02215

Dana Farber Cancer Institute, Boston

Sponsors
All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Repertoire Immune Medicines

INDUSTRY

NCT03815682 - RPTR-147 in Patients With Selected Solid Tumors and Lymphomas | Biotech Hunter | Biotech Hunter