Evaluation of Pain Sensitization in Rheumatoid Arthritis: Analysis on a Cohort of Tofacitinib Treated Patients

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

June 17, 2019

Primary Completion Date

April 28, 2023

Study Completion Date

April 28, 2023

Conditions
Rheumatoid Arthritis
Interventions
OTHER

Clinical examination

"* Number of painful joints,~* Number of swollen joints,~* Patient Global assessment VAS (0 - 100)~* and Physician Global assessment VAS (0 - 100)"

OTHER

Pain assessment

"* Pressure Pain Thresholds (PPTs),~* Mechanical Temporal Summation (MTS)~* and Diffuse Noxious Inhibitory Control (DNIC)"

OTHER

blood sample

18 ml whole blood for ELISA analysis and miRNAs detection

OTHER

Patient Reported Outcomes

"* Health Assessment Questionnaire (HAQ),~* Rheumatoid Arthritis Impact of Disease score (RAID),~* Daily joint pain intensity VAS (0-100),~* Hospital Anxiety and Depression scale~* and Coping Strategy Questionnaire."

Trial Locations (2)

Unknown

CHU de Bordeaux - Service de rhumatologie, Bordeaux

CHU de Limoges - service de rhumatologie, Limoges

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Pfizer

INDUSTRY

lead

University Hospital, Bordeaux

OTHER