A Nationwide Phase 2 Trial of Patients With Smoldering and Active Multiple Myeloma (MM)

PHASE2Enrolling by invitationINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

June 24, 2019

Primary Completion Date

January 31, 2024

Study Completion Date

January 31, 2028

Conditions
Multiple MyelomaSmoldering Multiple Myeloma
Interventions
DRUG

Carfilzomib

Carfilzomib will be administered intravenously three times per cycle (28 day cycles) for cycle 1-12. Thereafter twice per cycle for cycle 13-24

DRUG

Lenalidomide

Lenalidomide PO once daily on days 1-21 of a 28 day cycle

DRUG

Dexamethasone

Dexamethasone will be administered weekly

Trial Locations (1)

101

Landspitali University Hospital, Reykjavik

Sponsors

Collaborators (2)

All Listed Sponsors
collaborator

Amgen

INDUSTRY

collaborator

Celgene

INDUSTRY

collaborator

University of Iceland

OTHER

collaborator

Memorial Sloan Kettering Cancer Center

OTHER

lead

Landspitali University Hospital

OTHER

NCT03815279 - A Nationwide Phase 2 Trial of Patients With Smoldering and Active Multiple Myeloma (MM) | Biotech Hunter | Biotech Hunter