701
Participants
Start Date
January 28, 2019
Primary Completion Date
June 26, 2019
Study Completion Date
June 26, 2019
ColdZyme
"ColdZyme® Mouth Spray, a CE -marked device with the following composition of the spray solution: glycerol, purified water, cod trypsin, ethanol (\<1 %), calcium chloride, trometamol and menthol.~ColdZyme is a non-sterile mouth spray packaged in a primary container consisting of a 20 ml semi-transparent plastic bottle, pump, actuator (spray nozzle) and an actuator terminal cap."
ColdZyme Placebo
The placebo mouth spray solution has the following composition: ethanol (\<1 %), menthol and water. The placebo mouth spray is packaged in a primary container consisting of a 20 ml semitransparent plastic bottle, pump, actuator (spray nozzle) and an actuator terminal cap.
analyze & realize GmbH, Berlin
emovis GmbH, Berlin
Klinische Forschung Berlin-Mitte GmbH, Berlin
Klinische Forschung Berlin, Berlin
Polikum Institut GmbH, Berlin
Praxis Frau Barbara Grube, Berlin
Thomas Wünsche, Berlin
BioTeSys GmbH, Esslingen am Neckar
Praxis Dr. med. Gudrun Ruhland, Koßdorf
SIBAmed Studienzentrum GmbH und Co. KG, Leipzig
Lead Sponsor
Analyze & Realize
NETWORK
Enzymatica AB
INDUSTRY