5
Participants
Start Date
May 15, 2019
Primary Completion Date
June 24, 2020
Study Completion Date
June 24, 2021
Tofacitinib 5mg Oral Tablet [Xeljanz] 16 week trial
Tofacitinib 5mg oral table twice daily for 16 weeks
Spirometry
Spirometry testing at baseline, week 4, week 8, week 12, and week 16
RNA Sequencing
RNA sequencing test at baseline and week 16
Laboratory testing
Laboratory testing at baseline and weeks 2, 4, 8, 12 and 16
Corticosteroid
Taper corticosteroids starting at week 4
Tofacitinib 5mg [Xeljanz] 1 year open-label extension
After 16 weeks, subjects who meet the primary end-point will be permitted an optional one year open-label extension.
Oregon Health & Science University, Portland
Collaborators (1)
Pfizer
INDUSTRY
Oregon Health and Science University
OTHER