Focal Intraoperative Radiotherapy of Brain Metastases

PHASE2TerminatedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

May 2, 2019

Primary Completion Date

June 30, 2022

Study Completion Date

June 30, 2022

Conditions
Brain Metastases, AdultCentral Nervous System Metastases
Interventions
RADIATION

Intraoperative Radiotherapy

Intraoperative Radiotherapy with a mobile device (Intrabeam, Carl Zeiss AG) consisting of a small source of low energy x-rays (30-50 kV) mounted on a mechanical arm with six degrees of freedom. The resulting dose distribution is isotropic around the tip of the X-ray source. A set of spherical applicators with diameters ranging from 1.5 to 5 cm is available to connect to the source. The treatment time may vary from 20-30 minutes with the suggested dose of 18 Gy to the resection cavity to a depth of 1 mm.

Trial Locations (1)

01509-900

AC Camargo Cancer Center, São Paulo

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Carl Zeiss Meditec AG

INDUSTRY

lead

AC Camargo Cancer Center

OTHER

NCT03789149 - Focal Intraoperative Radiotherapy of Brain Metastases | Biotech Hunter | Biotech Hunter