NIMBUS: Nivolumab Plus Ipilimumab in Metastatic Hypermutated HER2-negative Breast Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

March 8, 2019

Primary Completion Date

September 30, 2021

Study Completion Date

December 30, 2025

Conditions
Breast Cancer
Interventions
DRUG

Nivolumab

Nivolumab is called an anti- PD-1 or a checkpoint inhibitor and is an antibody (a type of human protein) designed to allow the body's own immune system to destroy tumors

DRUG

Ipilimumab

Ipilimumab is called an anti-CTLA-4 and is a type of antibody that works to prevent the body's immune system from stopping to fight a specific cancer

Trial Locations (3)

15213

University of Pittsburgh Medical Center, Pittsburgh

75390

University of Texas Southwestern Medical Center, Dallas

02215

Dana-Farber Cancer Institute, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

Dana-Farber Cancer Institute

OTHER