159
Participants
Start Date
January 1, 2014
Primary Completion Date
December 31, 2014
Study Completion Date
June 1, 2015
Melatonin 1mg
1 mg/day 30 minutes before sleep
Essential Aminoacids (eAA)
4g/day of Essential Aminoacids during breakfast. Packets of powdered amino acid supplements (42.0% leucine, 14.0% lysine, 10.5% valine, 10.5% isoleucine, 10.5% threonine, 7.0% phenylalanine, and 5.5% other) were provided for the participants to be taken with water or milk, and they were instructed to take the 4-gram supplement once a day every day for 4 weeks.
Essential Aminoacids + melatonin
4g/day of Essential Aminoacids during breakfast + 1 mg/day of Melatonin 30 minutes before sleep. Packets of powdered amino acid supplements (42.0% leucine, 14.0% lysine, 10.5% valine, 10.5% isoleucine, 10.5% threonine, 7.0% phenylalanine, and 5.5% other) were provided for the participants to be taken with water or milk, and they were instructed to take the 4-gram supplement once a day every day for 4 weeks.
Placebo
an isocaloric amount of maltodextrin with the same flavor and appearance as the intervention product
Geriatric physical medicine and rehabilitation division at the Istituto Santa Margherita - Azienda di Servizi alla Persona di Pavia, Pavia
Azienda di Servizi alla Persona di Pavia
OTHER