Effects of SGLT-2 Inhibition on Myocardial Fibrosis and Inflammation as Assessed by Cardiac MRI in Patients With DM2

PHASE4CompletedINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

February 26, 2019

Primary Completion Date

November 16, 2022

Study Completion Date

November 16, 2022

Conditions
Type 2 Diabetes MellitusMyocardial FibrosisMyocardial Inflammation
Interventions
DRUG

dapagliflozin

Subjects will either receive 10mg tabs of dapagliflozin or identical looking placebo - inactive medication. Subjects have an equal chance of receiving dapagliflozin or placebo. Which treatment subjects receive is decided at random by a computer (purely by chance, like the tossing of a coin). Neither subjects nor the Study Site personnel will know which treatment subjects are assigned to. The study drug must be taken daily. The subject's other medications will not be changed by the study.

OTHER

Placebo

Placebo

Trial Locations (1)

98104

University of Washington, Seattle

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

University of Washington

OTHER