A Study to Evaluate MIV-818 in Patients With Liver Cancer Manifestations

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

53

Participants

Timeline

Start Date

September 5, 2018

Primary Completion Date

January 7, 2025

Study Completion Date

June 16, 2025

Conditions
Hepatocellular CarcinomaIntrahepatic CholangiocarcinomaLiver Metastases
Interventions
DRUG

MIV-818 (fostroxacitabine bralpamide) + pembrolizumab

MIV-818 - oral capsules; pembrolizumab - IV

DRUG

MIV-818 (fostroxacitabine bralpamide) + lenvatinib

MIV-818 - oral capsules; lenvatinib - oral capsules

Trial Locations (18)

2650

Antwerp University Hospital, Antwerp

3000

University Hospitals Gasthuisberg, Leuven

28009

Hospital General Universitario Gregorio Marañón, Madrid

Unknown

CHA Bundang Medical Center, Gyeonggi-do

Pusan National University Hospital, Pusan

Asan Medical Center, Seoul

Samsung Medical Center, Seoul

Seoul National University Hospital, Seoul

Severance Hospital, Seoul

Hospital Clinic Carrer Rosselló 161, Barcelona

Hospital Vall Hebrón, Barcelona

START Barcelona HM Nou Delfos, Barcelona

Hospital Universitario 12 de Octubre, Madrid

START Madrid-FJD, Madrid

Beatson West of Scotland Cancer Care, Glasgow

Guy's Hospital, Oncology and Clinical Trials, London

Northern Institute for Cancer Research, Newcastle upon Tyne

OX3 7LE

Chruchill Hospital, Cancer and Haematology Centre, Oxford

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Medivir

INDUSTRY

NCT03781934 - A Study to Evaluate MIV-818 in Patients With Liver Cancer Manifestations | Biotech Hunter | Biotech Hunter