550
Participants
Start Date
January 15, 2023
Primary Completion Date
September 1, 2025
Study Completion Date
October 1, 2025
Methotrexate
Participants in the intervention group will receive methotrexate along side prednisolone
Placebo
Participants in the control arm will receive placebo along side prednisolone
Prednisolone
Participants in both arm will receive prednisolone, which will be the same dosage: 40 mg (initial dose) decreasing dosage for 20 weeks
TMLI Bangladesh/ DBLM hospital, Dhaka
FIOCRUZ, Rio de Janeiro
ALERT, Addis Ababa
The Leprosy Mission Trust, Delhi
Bombay Leprosy Project, Mumbai
Soetomo Hospital, Surabaya
Anandaban Hospital, Kathmandu
Dr. Soetomo General Hospital
OTHER_GOV
The Leprosy Mission Trust, India
UNKNOWN
Alert Hospital, Ethiopia
OTHER
The Leprosy Mission Bangladesh
OTHER
Bombay Leprosy Project, India
UNKNOWN
Oswaldo Cruz Foundation
OTHER
Leprosy Research Initiative
UNKNOWN
The Leprosy Mission Nepal
OTHER
London School of Hygiene and Tropical Medicine
OTHER