ESTIMATION OF THE EFFECT OF MULTIPLE DOSE PF-06651600 ON THE PHARMACOKINETICS OF SINGLE DOSE MIDAZOLAM AND EFAVIRENZ

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

December 7, 2018

Primary Completion Date

January 27, 2019

Study Completion Date

February 21, 2019

Conditions

Healthy Subjects

Interventions

DRUG

PF-06651600

200 milligram (mg) PF-06651600 once daily (QD) orally for 11 days

DRUG

midazolam

single administration of midazolam 2 mg oral solution

DRUG

efavirenz

single administration of efavirenz 50 mg capsule

Trial Locations (1)

Pfizer New Haven Clinical Research Unit, New Haven