A Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB086550 in Participants With Advanced Solid Tumors

PHASE1CompletedINTERVENTIONAL
Enrollment

138

Participants

Timeline

Start Date

December 10, 2018

Primary Completion Date

November 17, 2023

Study Completion Date

November 17, 2023

Conditions
Solid Tumors
Interventions
DRUG

INCB086550

INCB086550 will be orally administered once or twice daily in continuous or intermittent dose schedules.

Trial Locations (25)

13385

Chu Hopital de La Timone, Marseille

19104

University of Pennsylvania Health System, Philadelphia

19107

Jefferson University Hospitals, Philadelphia

20007

Georgetown University Hospital, Washington D.C.

20089

Irrcs Instituto Clinico Humanitas, Rozzano

20133

Fondazione Irccs Istituto Nazionale Dei Tumori, Milan

20141

European Institute of Oncology, Milan

21401

Aamc Oncology and Hematology, Annapolis

31059

Institut Universitaire Du Cancer de Toulouse Oncopole, Toulouse

33612

H. Lee Moffitt Cancer Center and Research Institute Hospital, Tampa

34298

Icm Montpellier, Montpellier

37203

Sarah Cannon Research Institute, Nashville

53100

Azienda Ospedaliera Universitaria Senese Policlinico Santa Maria Alle Scotte, Siena

75005

Institut Curie, Paris

77030

Md Anderson Cancer Center, Houston

80131

Istituto Nazionale Tumori Irccs Fondazione Pascale, Napoli

01000

Institut Jules Bordet, Brussels

02650

Universitair Ziekenhuis Antwerpen (Uza), Edegem

09000

Universitair Ziekenhuis Gent, Ghent

03000

Universitaire Ziekenhuis Leuven - Gasthuisberg, Leuven

CB2 0QQ

Addenbrooke'S Hospital, Cambridge

SE1 9RT

Guys and St Thomas Nhs Foundation Trust, London

W12 0HS

Imperial College Healthcare Nhs Trust - Hammersmith Hospital, London

M20 4BX

The Christie Nhs Foundation Trust Uk, Manchester

S10 2SJ

Weston Park Hospital, Sheffield

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Incyte Corporation

INDUSTRY

NCT03762447 - A Study Exploring the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB086550 in Participants With Advanced Solid Tumors | Biotech Hunter | Biotech Hunter