Neoadjuvant PD-1 Blockade in Patients with Stage IIB/C Melanoma

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

May 6, 2019

Primary Completion Date

December 1, 2024

Study Completion Date

February 28, 2027

Conditions
Melanoma
Interventions
DRUG

Pembrolizumab

Pre-Surgery: Pembrolizumab, one 200mg dose; Post-Surgery: Pembrolizumab, 200 mg every 3 weeks.

PROCEDURE

Wide Excision and Sentinel Lymph Node (SLN) Biopsy

Wide excision and SLN biopsy and pathologic assessment of tissue will be performed per standard of care.

Trial Locations (3)

19104

Abramson Cancer Center of the University of Pennsylvania, Philadelphia

40202

University of Louisville, Louisville

77030

The University of Texas MD Anderson Cancer Center, Houston

All Listed Sponsors
lead

Abramson Cancer Center at Penn Medicine

OTHER

NCT03757689 - Neoadjuvant PD-1 Blockade in Patients with Stage IIB/C Melanoma | Biotech Hunter | Biotech Hunter