Investigation of Psychophysiological Response to Aversive Stimuli Over Time With Omega-3

NACompletedINTERVENTIONAL
Enrollment

133

Participants

Timeline

Start Date

August 31, 2011

Primary Completion Date

August 31, 2015

Study Completion Date

August 31, 2015

Conditions
Conduct DisorderADHDOppositional Defiant Disorder
Interventions
DIETARY_SUPPLEMENT

Omega-3

Omega-3 supplement is a highly concentrated fish oil brain booster supplement that helps compensate for the neurocognitive and brain dysfunction which acts as a predisposition to antisocial and violent behaviour. Individuals with antisocial personality disorder have been found to show an 11% reduction in gray matter in the prefrontal cortex (Raine et al. 2001), and structural prefrontal impairments are hypothesised to result in disinhibition of limbic subcortical structures that give rise to aggressive behaviour. Omega-3 (specifically DHA) is known to play a key role in neuronal structure and function.

DIETARY_SUPPLEMENT

Placebo Capsules

Children in this group will be given two placebo capsules twice daily; at breakfast and at the evening meal for a total period of 6 months.

All Listed Sponsors
lead

Yale-NUS College

OTHER

NCT03749824 - Investigation of Psychophysiological Response to Aversive Stimuli Over Time With Omega-3 | Biotech Hunter | Biotech Hunter