Palatability (Taste) of Oral Formulations of Bosutinib

PHASE1CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

November 22, 2018

Primary Completion Date

January 14, 2019

Study Completion Date

January 14, 2019

Conditions
CML
Interventions
DRUG

200 Mg capsules of bosutinib in Water solution

200 mg (4X50) Capsules in water

DRUG

bosunitib sorbitol

200 Mg of bosutinib sorbitol solution

DRUG

Bosutinib Mannitol

Bosutinib mannitol solution

DRUG

bosutinib in mannitol low sweet

bosutinib in mannitol solution low sweet

DRUG

bosutinib in mannitol high sweet

bosutinib in mannitol high sweet

DRUG

bosutinib taste low flavour

bosutinib solution low flavour

DRUG

bosutinib high flavour

bosutinib solution high flavour

DRUG

bosutinib capsules in applesauce

Bosutinib capsules in applesauce

DRUG

Bosutinib capsules in yogurt

bosutinib capsules in yogurt

DRUG

bosutinib capsules in water

sham comparator, bosutinb in water retest

DRUG

Bosutinib capsules in low sweet

bosutinib capsules in low sweet

DRUG

bosutinib capsules high sweet

Bosutinib capsules high sweet

DRUG

bosutinib capsules low flavour

Bosutinib capsules low flavour

DRUG

bosutinib capsules high flavour

bosutinib capsules in high flavour

Trial Locations (1)

B-1070

Pfizer Clinical Research Unit, Brussels

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Pfizer

INDUSTRY