A Study to Evaluate the Safety and Efficacy of JCAR017 in Pediatric Subjects With Relapsed/Refractory (r/r) B-cell Acute Lymphoblastic Leukemia (B-ALL) and B-cell Non-Hodgkin Lymphoma (B-NHL)

PHASE1/PHASE2TerminatedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

October 17, 2018

Primary Completion Date

January 26, 2024

Study Completion Date

January 26, 2024

Conditions
Precursor Cell Lymphoblastic Leukemia-LymphomaLymphoma, Non-Hodgkin
Interventions
DRUG

JCAR017

JCAR017

DRUG

Lymphodepleting

Lymphodepleting

DRUG

Fludarabine

Fludarabine

DRUG

Cyclophosphamide

Cyclophosphamide

Trial Locations (19)

10021

Local Institution - 160, New York

13005

Local Institution - 602, Marseille

13353

Local Institution - 501, Berlin

19104

Local Institution - 162, Philadelphia

20900

Local Institution - 301, Monza

28009

Local Institution - 250, Madrid

33701

Local Institution - 166, St. Petersburg

53226

Local Institution - 168, Wauwatosa

69008

Local Institution - 601, Lyon

75935

Local Institution - 600, Paris

77030

Local Institution - 165, Houston

91010

Local Institution - 163, Duarte

94063

Local Institution - 167, Redwood City

98105

Local Institution - 161, Seattle

75390-7208

Local Institution - 164, Dallas

D-60590

Local Institution - 500, Frankfurt

00165

Local Institution - 300, Roma

3584 CS

Local Institution - 400, Utrecht

08950

Local Institution - 251, Esplugues de Llobregat

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Celgene

INDUSTRY