Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma

NAActive, not recruitingINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

November 28, 2018

Primary Completion Date

December 31, 2023

Study Completion Date

January 1, 2027

Conditions
GliomaGlioma of BrainCancerPediatric CancerPediatric Brain TumorAstrocytomaGlioblastomaHemispheric
Interventions
OTHER

Specialized tumor board recommendation

Based on the molecular profile, the specialized tumor board will determine an individualized treatment recommendation for each patient using up to four FDA approved drugs. In special circumstances, Investigational new drug (IND) study agents may be used.

Trial Locations (12)

19104

The Children's Hospital Of Philadelphia, Philadelphia

20010

Children's National Medical Center, Washington D.C.

21218

Johns Hopkins University, Baltimore

32611

University of Florida, Gainesville

43205

Nationwide Children's Hospital, Columbus

55404

Children's Hospitals and Clinics of Minneapolis, Minneapolis

60611

Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago

63110

Washington University, St Louis

84112

University of Utah, Salt Lake City

92123

University of California, San Diego Rady Children's Hospital, San Diego

94158

University of California, San Francisco, San Francisco

98105

Seattle Children's Hospital, Seattle

All Listed Sponsors
collaborator

Pacific Pediatric Neuro-Oncology Consortium

OTHER

collaborator

The V Foundation for Cancer Research

OTHER

lead

University of California, San Francisco

OTHER

NCT03739372 - Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma | Biotech Hunter | Biotech Hunter