Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis

PHASE3CompletedINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

January 7, 2019

Primary Completion Date

May 29, 2020

Study Completion Date

June 30, 2022

Conditions
Recurrent Pericarditis
Interventions
DRUG

Rilonacept

Rilonacept 320 mg (or 4.4 mg/kg in pediatric participants ≥12 and \<18 years old) SC , followed by 160 mg (or 2.2 mg/kg in pediatric participants ≥12 and \<18 years old) injections once weekly

DRUG

Placebo

Placebo SC injections once weekly

Trial Locations (21)

3109

GenesisCare - Cardiology Research, Doncaster East

19067

Cardiology Consultants of Philadelphia, Yardley

23298

Virginia Commonwealth University, Richmond

30342

Arthritis and Rheumatology of Georgia, Atlanta

40664

HeartCare Partners Clinical Research Unit, Milton

44195

Cleveland Clinic, Cleveland

45229

Cincinnati Children's Hospital Medical Center, Cincinnati

55407

Minneapolis Heart Institute Foundation, Minneapolis

55902

Mayo Clinic - PPDS, Rochester

60644

The Loretto Hospital, Chicago

84107

Intermountain Healthcare, Murray

90048

Cedars-Sinai Medical Institute, Los Angeles

98122

Swedish Medical Center, Seattle

05401

University Of Vermont Medical Center, Burlington

Unknown

Bnai Zion Medical Center, Haifa

Shaare Zedek Medical Center, Jerusalem

Galilee Medical Center, Nahariya

Sheba Medical Center at Tel-Hashomer, Ramat Gan

Ospedale Pediatrico Bambino Gesù, Rome

ASST Fatebenefratelli Sacco - Ospedale Fatebenefratelli e Oftalmico, Milan

Azienda Ospedaliera Città della Salute e della Scienza di Torino, Turin

All Listed Sponsors
lead

Kiniksa Pharmaceuticals (UK), Ltd.

INDUSTRY

NCT03737110 - Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis | Biotech Hunter | Biotech Hunter