Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

November 15, 2018

Primary Completion Date

June 30, 2025

Study Completion Date

November 30, 2025

Conditions
Obstructive Sleep ApneaSpinal Cord Injuries
Interventions
OTHER

Mild intermittent hypoxia

Participants will be exposed to twelve two minute episodes of mild intermittent hypoxia 5 days a week for 3 weeks.

OTHER

Sham protocol

Participants will be exposed to twelve two minute episodes of sham mild intermittent hypoxia (i.e. room air) 5 days a week for 3 weeks.

OTHER

Continuous positive airway pressure (CPAP)

All participants will be treated with CPAP each night for a duration of 3 weeks.

Trial Locations (2)

48201

RECRUITING

John D Dingell VA Medical Center, Detroit

RECRUITING

Wayne State University, Detroit

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Wayne State University

OTHER