A Pragmatic Assessment of Influenza Vaccine Effectiveness in the DoD

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

15,449

Participants

Timeline

Start Date

November 6, 2018

Primary Completion Date

July 7, 2022

Study Completion Date

May 31, 2024

Conditions
InfluenzaInfluenza-like IllnessInfluenza Vaccines
Interventions
BIOLOGICAL

Egg based influenza vaccines

Participants will be randomly allocated to one of three vaccine types in accordance with standard clinical practices for those in the US military. All vaccines are FDA licensed for use in the United States.

BIOLOGICAL

Recombinant influenza vaccines

Participants will be randomly allocated to one of three vaccine types in accordance with standard clinical practices for those in the US military. All vaccines are FDA licensed for use in the United States.

BIOLOGICAL

Cell-culture based influenza vaccines

Participants will be randomly allocated to one of three vaccine types in accordance with standard clinical practices for those in the US military. All vaccines are FDA licensed for use in the United States.

Trial Locations (9)

20307

USU, Bethesda

20814

Walter Reed National Military Medical Center, Bethesda

21402

United States Naval Academy, Annapolis

23704

Naval Medical Center Portsmouth, Portsmouth

28310

Womack Army Medical Center, Fort Bragg

34800

Naval Medical Center San Diego, San Diego

78234

Brooke Army Medical Center, Fort Sam Houston

78243

Lackland Airforce Base, San Antonio

98431

Madigan Army Medical Center, Tacoma

Sponsors
All Listed Sponsors
collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

collaborator

Food and Drug Administration (FDA)

FED

collaborator

Defense Health Agency Immunization Healthcare Branch

UNKNOWN

collaborator

US Department of Defense Armed Forces Health Surveillance Center

FED

collaborator

Naval Health Research Center

FED

collaborator

United States Air Force School of Aerospace Medicine

FED

collaborator

Uniformed Services University of the Health Sciences

FED

lead

Henry M. Jackson Foundation for the Advancement of Military Medicine

OTHER

NCT03734237 - A Pragmatic Assessment of Influenza Vaccine Effectiveness in the DoD | Biotech Hunter | Biotech Hunter