(PIONEER) Study to Evaluate Efficacy and Safety of Avapritinib (BLU-285), A Selective KIT Mutation-targeted Tyrosine Kinase Inhibitor, Versus Placebo in Patients With Indolent Systemic Mastocytosis

University Hospital Antwerp, Edegem

University Hospital Basel, Basel

Herbert Irving Comprehensive Cancer Center, New York

Charité Universitätsmedizin Berlin, Berlin

Hôpital de la Timone, Service de dermatologie, Marseille

Fondazione IRCCS Ca' Granda Ospedale Maggiore Poloclinico, UOC Ematologia, Milan

University Clinic Hamburg Eppendorf, University Cancer Center Hamburg (UCCH), Hamburg

Virginia Commonwealth University Medical Center, Richmond

Universitätsklinikum Schleswig-Holstein, Hämatologie/Onkologie, Lübeck

Duke University Health System (DUHS), Durham

Winship Cancer Institute, Emory University, Atlanta

CHU Toulouse Larrey, CEREMAST, Service de Dermatologie et Allergologie cutanée, Toulouse

Mayo Clinic Florida, Jacksonville

H. Lee Moffitt Cancer Center, Tampa

University of Alabama at Birmingham, Birmingham

Azienda Ospedaliera Universitaria Integrata di Verona, Verona

A.O.U di Bologna - IRCCS, Istituto di Ematologia Lorenzo e Ariosto Seragnoli, Ematologia, Bologna

University Hospitals Cleveland Medical Center, Cleveland

lnstituto de Estudios de Mastocitosis de Castilla la Mancha, Hospital Virgen del Valle - Complejo Hospitalario de Toledo, Toledo

Michigan Medicine, University of Michigan, Ann Arbor

Uniklinik RWTH Aachen, Aachen

Universitätsklinik Mainz, Universitäts-Hautklinik, Clinical Research Center, Mainz

Mayo Clinic, Rochester

Rush University Medical Center, Chicago

Washington University School of Medicine, St Louis

University of Kansas Hospital, Kansas City

Universitätsmedizin Mannheim, III. Medizinische Klinik, Mannheim

Hôpital Pitié-Salpêtrière, Service de Dermatologie, Paris

University of Texas, MD Anderson Cancer Center, Houston

Klinikum rechts der Isar, Technische Universität München, Munich

Huntsman Cancer Institute, Salt Lake City

A.O. OO.RR. S.Giovanni di Dio e Ruggi d'Aragona, University of Salerno, Salerno

Mayo Clinic Hospital, Phoenix

Stanford Cancer Institute, Stanford

Brigham & Women's Hospital, Boston

Dana Farber Cancer Institute, Boston

Tom Baker Cancer Centre, Calgary

University of Alberta Hospital, Edmonton

St. Michael's Hospital, Toronto

Odense Universitetshospital, ORCA/Allergicentret, Hudafdeling I og Allergicenter, Odense

University Medical Center Groningen (UMCG), Groningen

Erasmus Medical Center, Rotterdam

Oslo Universitetssykehus, Rikshospitalet, Department of Hematology, Oslo

Hospital Universitari Vall d'Hebron, Barcelona

Karolinska University Hospital, Hematologimottagningen R51, Stockholm

Akademiska sjukhuset, Hematologmottagningen/101A, Uppsala

NHS Greater Glasgow and Clyde, Beatson West of Scotland Cancer Centre, Glasgow

Guy's and St Thomas' NHS Foundation Trust - Guy's Hospital, London

Clatterbridge Cancer Centre NHS Foundation Trust, Metropolitan Borough of Wirral