NCT03728478 - STep-up and Step-down Therapeutic Strategies in Childhood ARthritiS | Biotech Hunter

Enrollment

260

Participants

Timeline

Start Date

May 29, 2019

Primary Completion Date

February 28, 2025

Study Completion Date

February 28, 2025

Conditions

Oligoarthritis, JuvenilePolyarthritis, Juvenile, Rheumatoid Factor Negative

Interventions

DRUG

Etanercept

Patients will receive etanercept subcutaneously at a dose of 0.8 mg/kg weekly (up to a maximum dose of 50 mg weekly).

DRUG

Methotrexate

Methotrexate will be administered subcutaneously, in a single weekly dose of 15 mg/m2 (max 20 mg).

DRUG

Intra-articular corticosteroid injections

Triamcinolone hexacetonide and methylprednisolone acetate doses depend on the affected joint.

Trial Locations (1)

RECRUITING

IRCCS Istituto Giannina Gaslini, Genova