Nivolumab and Temozolomide in Treating Patients With Recurrent or Refractory Small-Cell Lung Cancer or Advanced Neuroendocrine Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

December 31, 2018

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2026

Conditions
Grade I Neuroendocrine CarcinomaGrade II Neuroendocrine CarcinomaGrade III Neuroendocrine CarcinomaMetastatic Neuroendocrine CarcinomaNeuroendocrine CarcinomaRecurrent Small Cell Lung CarcinomaRefractory Small Cell Lung CarcinomaLung Cancer Stage IVLarge Cell Neuroendocrine CarcinomaNeuroendocrine TumorsSmall Cell Lung Cancer MetastaticSmall-cell Lung Cancer
Interventions
BIOLOGICAL

Nivolumab

Given IV

DRUG

Temozolomide

Given PO

Trial Locations (2)

43210

Ohio State University Comprehensive Cancer Center-COHORT 1, Columbus

Ohio State University Comprehensive Cancer Center-COHORT 2, Columbus

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

Dwight Owen

OTHER