NCT03726268 - Optimizing Outpatient Anesthesia (OSPREy-Outpatient Surgery Pain Relief Enhancement) | Biotech Hunter

Enrollment

907

Participants

Timeline

Start Date

November 29, 2018

Primary Completion Date

July 30, 2023

Study Completion Date

January 30, 2024

Conditions

Opioid UsePain, Postoperative

Interventions

DRUG

Methadone

"Dose is 0.15-0.3 mg/kg IV methadone HCl given intraoperatively and in the immediate post-operative period. Intraoperative methadone doses are 15 mg in short-stay, anticipated next-day discharge patients (10 mg if ≤55kg), and 10 mg in same-day surgery patients."

DRUG

Fentanyl

Given per clinical provider discretion intraoperatively and in the immediate post-operative period (while patient remains in the post anesthesia care unit (PACU)).

DRUG

Hydromorphone

Given per clinical provider discretion intraoperatively and in the immediate post-operative period (while patient remains in the post anesthesia care unit (PACU)).

DRUG

Morphine

Given per clinical provider discretion intraoperatively and in the immediate post-operative period (while patient remains in the post anesthesia care unit (PACU)).

DRUG

Sufentanil

Given per clinical provider discretion intraoperatively and in the immediate post-operative period (while patient remains in the post anesthesia care unit (PACU)).

Trial Locations (1)

27710

Duke University Medical Center, Durham