The Bern Heart and Brain Interaction Study - Interaction Between Brain and Heart in Acute Ischemic Stroke

RecruitingOBSERVATIONAL
Enrollment

220

Participants

Timeline

Start Date

December 1, 2018

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2026

Conditions
Acute Stroke
Interventions
PROCEDURE

Short cardiovascular MRI (CMR)

A short CMR without additional contrast administration will be performed immediately after the routine brain MRI (at admission or after 24h).

PROCEDURE

Adenosine-perfusion cardiovascular MRI (CMR)

An adenosine-perfusion CMR using contrast medium (gadolinium) will be performed in all patients (except group 1) between 48h and 6 days after admission.

PROCEDURE

Blood draw

"The following study-specific parameters will be tested: neuropeptide Y 1-36, neuropeptide Y 3-36, total plasma metanephrines, metabolomics analysis~Time points for blood draw: at admission (routine), 3h (routine), 24h (routine), 48h, 72h and 3 months."

PROCEDURE

Urine (collection over 24h)

"The following study-specific parameters will be tested: catecholamines.~Time points for collection: at 24h, 72h, and 3 months"

Trial Locations (1)

3010

RECRUITING

Bern University Hospital - Inselspital, Bern

All Listed Sponsors
lead

Insel Gruppe AG, University Hospital Bern

OTHER