A Study of a FimH Blocker, EB8018, in Crohn's Disease Patients

PHASE1CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

March 7, 2018

Primary Completion Date

November 12, 2019

Study Completion Date

December 4, 2019

Conditions
Crohn Disease
Interventions
DRUG

EB8018 (First-in-class FimH blocker)

"Drug: EB8018 EB8018 is an orally administered, first-in-class, FimH blocker~• In Part 1, a single oral dose of EB8018 3000 mg will be administered to the 2 sentinel patients in the morning on Day 1. In the multi-dose treatment period (part 1 and 2), multiple oral doses of EB8018 1500 mg will be administered to 2 + 6 patients BID (in the morning and evening) on Days 1 through 13."

Trial Locations (5)

Unknown

Medical University Vienna, Vienna

Hôpital Claude Huriez, Lille

Hôpital de l'Archet 2, Nice

Universitätsklinikum Schleswig-Holstein Campus Kiel, Kiel

Istituto Clinico Humanitas, Rozzano

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Enterome

INDUSTRY