CVD 38000: Study of Responses to Vaccination With Typhoid and/or Cholera

PHASE4RecruitingINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

November 5, 2018

Primary Completion Date

May 31, 2029

Study Completion Date

May 31, 2029

Conditions
Typhoid and/or Cholera Vaccination
Interventions
DRUG

Vivotif Typhoid Oral Vaccine

The 4 doses (1 capsule each) will be administered on alternate days, e.g., days 0, 2, 4, and 7 (± 1 day) under the supervision of the study coordinator(s).

DRUG

Vaxchora

One dose. Approximately 100 mL of cool or room temperature purified bottled water is placed into a clean disposable cup. The contents of the buffer sachet are added to the water and stirred. Then the contents of the active (lyophilized vaccine) sachet are added to the water and stirred for approximately 30 seconds. The reconstituted mixture should be completely ingested within 15 minutes.

Trial Locations (1)

21201

RECRUITING

University of Maryland, Baltimore, Center for Vaccine Development and Global Health, Baltimore

All Listed Sponsors
lead

University of Maryland, Baltimore

OTHER