Lenalidomide in Anti-MAG Neuropathy: Phase 1b Study

PHASE1TerminatedINTERVENTIONAL
Enrollment

11

Participants

Timeline

Start Date

September 10, 2018

Primary Completion Date

February 28, 2022

Study Completion Date

February 28, 2022

Conditions
Demyelinating Sensorimotor Neuropathy
Interventions
DRUG

Lenalidomide

"Dose Escalation~Patients in the dose escalation phase will receive oral treatment with:~Lenalidomide: 10, 15, or 25 mg on Days 1-21 of every 28-day cycle Dexamethasone: 20mg on Days 1,8,15 and 22~Starting doses of Lenalidomide will be assigned at the time of registration.~Dose Expansion~Once the MTD has been established or determined, 8 additional patients will be treated at the MTD of lenalidomide at the same schedule as above. Dexamethasone will be given at the same dose as in the dose escalation portion of the study."

Trial Locations (2)

43210

The Ohio State University Medical Center, Columbus

48109

University of Michigan, Ann Arbor

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Celgene Corporation

INDUSTRY

collaborator

University of Michigan

OTHER

lead

Ohio State University

OTHER