NCT03698695 - A Pharmacodynamics, Safety, and Pharmacokinetics Study of THN201 Versus Donepezil in Healthy Male Volunteers | Biotech Hunter

Enrollment

152

Participants

Timeline

Start Date

September 27, 2018

Primary Completion Date

October 20, 2019

Study Completion Date

December 20, 2019

Conditions

Cognitive ImpairmentAlzheimer Disease

Interventions

DRUG

THN 201

THN 201: Donepezil 5 mg and Mefloquine 10 mg/d

DRUG

Donepezil

Donepezil 5 mg/d and Mefloquine placebo

DRUG

Placebo

Donepezil placebo and Mefloquine placebo

Trial Locations (7)

CHU Bordeaux, Bordeaux

CHU Clermont Ferrand, Clermont-Ferrand

CHU Grenoble, Grenoble

CHU Lille, Lille

CHU Marseille, Marseille

Biotrial, Rennes

CHU Toulouse, Toulouse