41
Participants
Start Date
October 1, 2013
Primary Completion Date
June 1, 2018
Study Completion Date
June 1, 2018
Regorafenib
Regorafenib is administered at dose of 120 mg daily for 3 weeks in a 4-week cycle
UGT1A1 genotyping (TA6/TA6)
The dosage of irinotecan in FOLFIRI is escalated from 180mg/m2 to 260 mg/m2
UGT1A1 genotyping (TA6/TA7)
The dosage of irinotecan in FOLFIRI is escalated from 180mg/m2 to 240 mg/m2
UGT1A1 genotyping (TA7/TA7)
The dosage of irinotecan in FOLFIRI is escalated from 120mg/m2 to180 mg/m2
Chung-Ho Memorial Hospital, Kaohsiung Medical University:, Kaohsiung City
Kaohsiung Medical University Chung-Ho Memorial Hospital
OTHER