A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

69

Participants

Timeline

Start Date

October 1, 2018

Primary Completion Date

October 31, 2026

Study Completion Date

October 31, 2026

Conditions
Metastatic CancerMelanoma CancerLung CancerBladder CancerRenal CancerHead/Neck Cancers
Interventions
RADIATION

Stereotactic Body Radiotherapy

(27 Gy over 3 fractions)

BIOLOGICAL

Ipilimumab, Nivolumab, Pembrolizumab or Atezolizumab

The checkpoint inhibitor that the patient was already receiving should be continued according to the standard schedule and dose of administration as determined by the treating physician. Immune Checkpoint Inhibitors include Ipilimumab (Melanoma) Nivolumab (Melanoma, Renal, NSCLC), Pembrolizumab (Melanoma, NSCLC), Atezolizumab (Bladder)

Trial Locations (10)

10065

Memorial Sloan Kettering Cancer Center, New York

10604

Memorial Sloan Kettering Westchester, Harrison

11553

Memorial Sloan Kettering Nassau, Uniondale

11570

Memorial Sloan Kettering Rockville Centre, Rockville Centre

11725

Memorial Sloan Kettering Commack, Commack

18103

Lehigh Valley Health Network, Allentown

06102

Hartford Healthcare, Hartford

07920

Memorial Sloan Kettering Basking Ridge, Basking Ridge

07748

Memorial Sloan Kettering Monmouth, Middletown

07645

Memorial Sloan Kettering Bergen, Montvale

All Listed Sponsors
lead

Memorial Sloan Kettering Cancer Center

OTHER

NCT03693014 - A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors | Biotech Hunter | Biotech Hunter