Phase 1, Safety and Bronchopulmonary PK Study in Healthy Volunteers

PHASE1CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

November 26, 2018

Primary Completion Date

June 30, 2019

Study Completion Date

December 18, 2019

Conditions
Healthy Subjects
Interventions
DRUG

TP-6076

The dose planned to be administered in this study is an iv infusion of 30 mg TP 6076 q24h for 4 consecutive days (starting on Day 1 and ending on Day 4).

PROCEDURE

Bronchoalveolar lavage

Subjects will be randomized to undergo a BAL at a single time point: either 2, 4, 8, or 24 hours after the start of the final TP-6076 iv infusion on Day 4.

Trial Locations (1)

Unknown

Hammersmith Medicines Research, London

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

PRA Health Sciences

INDUSTRY

lead

Tetraphase Pharmaceuticals, Inc

INDUSTRY