42
Participants
Start Date
January 4, 2019
Primary Completion Date
September 30, 2025
Study Completion Date
January 31, 2032
rhIL-7-hyFc
-Given by intramuscular injection
Placebo
-Given by intramuscular injection
Temozolomide
-Standard of care
Radiation therapy
-Standard of care
Blood sample
"* Week 1 (prior to the 1st dose of rhIL-7-hyFc)~* Week 2 (one week after rhIL-7-hyFc)~* Week 3 (two weeks after rhIL-7-hyFc)~* Week 4 (three weeks after rhIL-7-hyFc)~* Week 13 (prior to the 2nd dose of rhIL-7-hyFc)~* Week 14 (one week after rhIL-7-hyFc)~* Week 16 (three weeks after rhIL-7-hyFc) - optional~* Week 45 (eight weeks after the last dose of rhIL-7-hyFC)~* If ADA or NADA is observed in week 45, additional blood collections will be required every 2 months in order to monitor ADA/NADA levels until it decreases to the basal level~* At the time of tumor progression"
Washington University School of Medicine, St Louis
Collaborators (1)
NeoImmuneTech
INDUSTRY
The Foundation for Barnes-Jewish Hospital
OTHER
Washington University School of Medicine
OTHER