Ribociclib and Letrozole Treatment in Ovarian Cancer

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

51

Participants

Timeline

Start Date

December 14, 2018

Primary Completion Date

December 23, 2024

Study Completion Date

December 31, 2026

Conditions
Low Grade Serous Carcinoma
Interventions
DRUG

Ribociclib

600 mg by mouth daily for 21 days followed by 7 days off treatment

DRUG

Letrozole

2.5 mg by mouth daily

Trial Locations (27)

15224

Western Pennsylvania Hospital/West Penn Hospital, Pittsburgh

19090

Abington Memorial Hospital, Willow Grove

30342

Northside Hospital, Atlanta

32610

UF Heath, Gainesville

33612

Moffitt Cancer Center, Tampa

43210

The Ohio State Comprehensive Cancer Center, Columbus

45459

Miami Valley Hospital, Centerville

46260

Saint Vincent Hospital and Health Care Center, Inc., Indianapolis

48106

St. Joseph Mercy Hospital Cancer Care Center, Ann Arbor

55905

Mayo Clinic - Rochester, Rochester

60201

NorthShore University HealthSystem, Evanston

73104

University of Oklahoma Health Sciences Center, Oklahoma City

74146

Oklahoma Cancer Care Specialists and Research Institute , LLC, Tulsa

75235

Parkland Health and Hospital System, Dallas

75390

University of Texas Southwestern Medical Center, Dallas

77030

MD Anderson Cancer Center, Houston

Memorial Hermann Texas Medical Center - Texas Medical Center, Houston

77070

Houston Methodist Willowbrook Hospital, Houston

77479

Houston Methodist Hospital, Houston

Houston Methodist Sugar Land Hospital, Sugar Land

87008

New Mexico Cancer Care Alliance/University of New Mexico Comprehensive Cancer Center, Albuquerque

Southwest Gynecologic Oncology Associates, Albuquerque

94158

University of California, San Francisco, San Francisco

05055

Dartmouth-Hitchcock Medical Center, Lebanon

07601

Hackensack University Medical Center, Hackensack

07540

The Valley Hospital Inc., Ridgewood

02905

Women & Infants Hospital, Providence

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Novartis

INDUSTRY

lead

Gynecologic Oncology Group

NETWORK

NCT03673124 - Ribociclib and Letrozole Treatment in Ovarian Cancer | Biotech Hunter | Biotech Hunter