Ipilimumab and Nivolumab in Recurrent Extensive Stage Small Cell Lung Cancer After Receiving Platinum-based Chemotherapy

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

December 6, 2018

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Small Cell Lung Cancer
Interventions
DRUG

Combination immunotherapy with Ipilimumab and Nivolumab

Patients will be treated with nivolumab 1 mg/kg and ipilimumab 3 mg/kg, starting on Day 1. Patients will receive 4 doses of each nivolumab and ipilimumab and then will receive nivolumab 240 mg starting week 13 (day 85) every 2 weeks until progression, unacceptable toxicity, withdrawal of consent, or the study ends, whichever occurs first.

Trial Locations (1)

06510

Yale University, Yale Cancer Center, New Haven

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bristol-Myers Squibb

INDUSTRY

lead

Yale University

OTHER