Clinical Trial for Patients With a Stage IV Childhood Renal Tumor, Comparing Upfront Vincristine, Actinomycin-D and Doxorubicin (Standard Arm) With Upfront Vincristine, Carboplatin and Etoposide (Experimental Arm)

PHASE3RecruitingINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

February 3, 2023

Primary Completion Date

October 3, 2028

Study Completion Date

October 3, 2033

Conditions
Childhood Renal Tumor
Interventions
DRUG

treatment Vincristin

1 x Vincristin 1,5mg/m² iv bolus day 1 in week 1,2,3,4,5,6

DRUG

treatment Actinomycin-D

1 x Actinomycin D 45µg/kg iv bolus day 1 in week 1, 3, 5

DRUG

treatment Doxorubicin

1 x Doxorubicin 50mg/m² 6h Infusion day 1 in week 1,5

DRUG

treatment Carboplatin

1 x Carboplatin 200 mg/m² 1h infusion day 1,2,3 in week 1,4

DRUG

Etoposide

1 x Etoposide 100mg/m² 1h infusion day 1,2,3 in week 1,4

Trial Locations (1)

Unknown

RECRUITING

Assistance Publique Hopitaux de Marseille, Marseille

All Listed Sponsors
collaborator

German Society for Pediatric Oncology and Hematology GPOH gGmbH

OTHER

lead

Assistance Publique Hopitaux De Marseille

OTHER