Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic Brain Injury

NAActive, not recruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

July 1, 2023

Primary Completion Date

August 30, 2025

Study Completion Date

September 30, 2029

Conditions
MTBI - Mild Traumatic Brain Injury
Interventions
BEHAVIORAL

PATH + DigitMemory (DM) neurotraining

Improve visual timing and sensitivity in the dorsal stream. The mTBI subject will sit 57 cm in front of a computer monitor. During the presentation, the bars in the 'fish-shaped' window in the center of the screen formed by a sinusoidal grating, move left or right very briefly. When the screen goes blank, the subject reports which way the center pattern moved by pushing the left or right arrow key. A brief tone is presented after incorrect responses. The program adaptively changes the contrast of the test pattern so that the subject detects motion at lowest contrast possible. A sequence of patterns in each training cycle that are designed to optimally activate magnocellular neurons are shown to the subject. There are two programs, the first measures the contrast needed to see one direction of movement, and the second program measures the contrast needed to see two directions of movement, requiring memory. Both are followed by digit memory exercises.

Trial Locations (2)

92075

Perception Dynamics Institute, Solana Beach

92121

University of California at San Diego, San Diego

All Listed Sponsors
collaborator

University of California, San Diego

OTHER

collaborator

University of South Alabama

OTHER

collaborator

University of California, Riverside

OTHER

lead

Perception Dynamics Institute

INDUSTRY

NCT03655782 - Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic Brain Injury | Biotech Hunter | Biotech Hunter