Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

142

Participants

Timeline

Start Date

October 2, 2020

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Cirrhosis
Interventions
DRUG

Placebo Oral Tablet

Placebo taken once nightly at bed time.

DRUG

Simvastatin 40mg

Simvastatin 40mg taken once nightly at bed time.

Trial Locations (11)

10468

James J. Peters VA Medical Center, Bronx, NY, The Bronx

11209

Brooklyn Campus of the VA NY Harbor Healthcare System, Brooklyn, NY, Brooklyn

19106

Philadelphia MultiService Center, Philadelphia, PA, Philadelphia

23249

Hunter Holmes McGuire VA Medical Center, Richmond, VA, Richmond

40206

Robley Rex VA Medical Center, Louisville, KY, Louisville

77030

Michael E. DeBakey VA Medical Center, Houston, TX, Houston

94121

San Francisco VA Medical Center, San Francisco, CA, San Francisco

98108

VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle

06516

VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven

02130

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston

19104-4551

Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia

All Listed Sponsors
lead

VA Office of Research and Development

FED