Effect of the CYP2C19 Polymorphism in Helicobacter Pylori Eradication

PHASE4CompletedINTERVENTIONAL
Enrollment

133

Participants

Timeline

Start Date

September 10, 2012

Primary Completion Date

August 8, 2015

Study Completion Date

August 8, 2015

Conditions
CYP2C19 PolymorphismH.Pylori InfectionTherapy
Interventions
DRUG

amoxicillin clarithromycin omeprazole 1

Patients in this received triple standard therapy for eradication of H.pylori with standard doses of proton pump inhibitor (omeprazole), in combination with amoxicillin and clarithromycin in absence of antibiotic resistance.

DRUG

amoxicillin clarithromycin omeprazole 2

The treatment for patients in this group was prescribing triple standard therapy for H.pylori eradication with amoxicillin and clarithromycin in absence of antibiotic resistance but with different doses of proton pump inhibitor (omeprazole) according to CYP2C19 genotype in each patients.

All Listed Sponsors
collaborator

Universidad Nacional de Colombia

OTHER

lead

Javeriana University

OTHER

NCT03650543 - Effect of the CYP2C19 Polymorphism in Helicobacter Pylori Eradication | Biotech Hunter | Biotech Hunter