A Study to Investigate the Pharmacokinetics (PK) of Modified Release (MR) Prototype Coated Tablet Formulations of GSK2982772

PHASE1CompletedINTERVENTIONAL
Enrollment

33

Participants

Timeline

Start Date

September 26, 2018

Primary Completion Date

May 7, 2019

Study Completion Date

May 7, 2019

Conditions
Autoimmune Diseases
Interventions
DRUG

GSK2982772 Modified Release

GSK2982772 MR will be available as MR prototype coated tablet with unit dose strength of 240 mg in Part A. In Part B, GSK2982772 MR prototype coated tablet with unit dose strength of 120 mg (may be changed following interim review of Part B) will be administered by subjects. GSK2982772 MR will be administered orally with 240 milliliter (mL) of water.

DRUG

GSK2982772 Immediate Release

In part A, GSK2982772 IR tablet will be available with unit dose strength of 30 mg and the total dose administered by subjects will be 240 mg (8 tablets of dose strength 30 mg) orally with 240 mL of water

Trial Locations (1)

NG11 6JS

GSK Investigational Site, Nottingham

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Quotient Sciences

INDUSTRY

lead

GlaxoSmithKline

INDUSTRY

NCT03649412 - A Study to Investigate the Pharmacokinetics (PK) of Modified Release (MR) Prototype Coated Tablet Formulations of GSK2982772 | Biotech Hunter | Biotech Hunter