Clinical Study on Strategy for Refractory Henoch-Schönlein Purpura

NARecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

September 1, 2019

Primary Completion Date

February 27, 2026

Study Completion Date

October 30, 2026

Conditions
Henoch-Schönlein Purpura
Interventions
DRUG

Methylprednisolone

1.methylprednisolone pulse (15-30mg/kg/d) for 3 days with continued oral prednisolone(2mg/kg/d) 2.if the patients still complain abdominal pain and feel abdominal tenderness on the third day after intervention , patients would be given IVIG(2g/kg/d)as a change

DRUG

IVIG

1\. IVIG 2g/kg and oral prednisolone 2mg/kg/d 2.if the patients still complain abdominal pain and feel abdominal tenderness on the third day after intervention , patients would be given methylprednisolone pulse (15-30mg/kg/d) for 3 days

DRUG

other basic supportive treatment

"1. Omeprazole 0.8mg/kg.d.The maximum dose is less than 40mg per day~2. Low molecular weight heparin calcium 50IU/kg.d"

Trial Locations (3)

Unknown

RECRUITING

Children's Hospital of Fudan University, Shanghai

NOT_YET_RECRUITING

Children's Hospital of Shanghai, Shanghai

NOT_YET_RECRUITING

Shanghai Children's Medical Centre, Shanghai

All Listed Sponsors
collaborator

Shanghai Children's Hospital

OTHER

collaborator

Shanghai Children's Medical Center

OTHER

lead

Children's Hospital of Fudan University

OTHER