Evaluation of Patients With Knee Osteoarthritis Receiving a Prosthesis

CompletedOBSERVATIONAL
Enrollment

22

Participants

Timeline

Start Date

May 31, 2013

Primary Completion Date

April 30, 2016

Study Completion Date

December 31, 2016

Conditions
Osteoarthritis, KneePerfusionBone MarrowMagnetic Resonance Imaging
Interventions
DIAGNOSTIC_TEST

Clinical evaluation

Functional scores for the pathological joint will be determined

DIAGNOSTIC_TEST

Radiology

DIAGNOSTIC_TEST

Dynamic contrast-enhanced magnetic resonance imaging

Patients will be examined using a 3T MR scanner (MR 750W, General Electrics, Milwaukee, WI) with a dedicated knee coil. Subchondral bone marrow vascularization in medial and lateral femorotibial compartments will be assessed with DCE-MRI and lesions will be graded on MR images.

DIAGNOSTIC_TEST

Evaluation of histological status

Upper tibial resection pieces will be collected and the vascularization will be determined according to the OARSI score

All Listed Sponsors
collaborator

Institut de Prévention et de Recherche sur l'Ostéoporose

UNKNOWN

lead

Lille Catholic University

OTHER

NCT03644420 - Evaluation of Patients With Knee Osteoarthritis Receiving a Prosthesis | Biotech Hunter | Biotech Hunter