Clinical Study of ET019002-T Cell Therapy for Refractory/Relapsed B-Cell Malignancies

EARLY_PHASE1UnknownINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

August 19, 2018

Primary Completion Date

August 19, 2020

Study Completion Date

September 20, 2020

Conditions
B-Cell Malignancies
Interventions
BIOLOGICAL

Low dose ET019002- T Cells

ET019002- T Cells are autologous T cells transduced expressing a novel anti-CD19 (ET019002) chimeric antigen receptor,and are administered by intravenous infusion with the dose of 0.75×10\*6/kg.

BIOLOGICAL

Middle dose ET019002- T Cells

ET019002- T Cells are autologous T cells transduced expressing a novel anti-CD19 (ET019002) chimeric antigen receptor,and are administered by intravenous infusion with the dose of 1.5×10\*6/kg.

BIOLOGICAL

High dose ET019002- T Cells

ET019002- T Cells are autologous T cells transduced expressing a novel anti-CD19 (ET019002) chimeric antigen receptor,and are administered by intravenous infusion with the dose of 3.0×10\*6/kg.

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Eureka Therapeutics Inc.

INDUSTRY

lead

First Affiliated Hospital Xi'an Jiaotong University

OTHER