Risk Prediction for Alzheimer Dementia With Brain Imaging and Genetics

NAWithdrawnINTERVENTIONAL
0
Timeline

Start Date

January 1, 2019

Primary Completion Date

January 1, 2021

Study Completion Date

January 1, 2021

Conditions
Alzheimer DementiaPosttraumatic Stress DisorderTraumatic Brain Injury
Interventions
DEVICE

MRI

You will be asked to undergo a scan of your brain called an MRI. The MRI scan can measure the functioning of your brain.

DEVICE

PET

You will be asked to undergo a scan of brain called a positron emission tomography (PET) scan. The PET scan is a test that uses radioactive glucose (sugar) and a computer to create images of how your brain is functioning. Abnormal cells in the body use glucose at a different rate than normal cells and this allows the scanner to create a detailed picture of how your body is working.

DEVICE

18F-Florbetapir

At the Duke University PET Center you will be in a quiet dimly lit space with only ambient room sound, with your eyes open and ears unplugged. Your safety will be monitored by a physician and nurse. 18F-florbetapir will be administered to you as a bolus injection through a peripheral vein followed by a flush and 10 minute continuous brain PET imaging will begin 50 minutes post-injection.

DEVICE

Radioligand 18F-AV-1451

At the Duke University PET Center you will be in a quiet dimly lit space with only ambient room sound, with your eyes open and ears unplugged. Your safety will be monitored by a physician and nurse. 18F-florbetapir will be administered to you as a bolus injection through a peripheral vein followed by a flush and 10 minute continuous brain PET imaging will begin 50 minutes post-injection.

Trial Locations (1)

27705

Durham VA, Durham

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Duke University

OTHER