Evaluation of the Safety and Efficacy of TLD in Patients with COPD

NAActive, not recruitingINTERVENTIONAL
Enrollment

464

Participants

Timeline

Start Date

May 23, 2019

Primary Completion Date

October 1, 2024

Study Completion Date

September 30, 2028

Conditions
COPD
Interventions
DEVICE

Targeted Lung Denervation (TLD)

Targeted Lung Denervation (TLD) Therapy is a bronchoscopically guided, minimally invasive procedure using the Nuvaira™ Lung Denervation System.

OTHER

Optimal Medical Care

Taking regular maintenance medication that minimally includes a long-acting muscarinic antagonist (LAMA) and a long-acting beta2-agonist (LABA).

Trial Locations (33)

15219

University of Pittsburgh Medical Center (UPMC), Pittsburgh

19140

Temple Lung Center, Philadelphia

27710

Duke University, Durham

28374

First Health of the Carolinas, Pinehurst

29425

Medical University of South Carolina (MUSC), Charleston

31400

Hopital Larrey, Toulouse

32204

Ascension St. Vincent's, Jacksonville

35294

University of Alabama at Birmingham (UAB) Lung Health Center, Birmingham

38043

CHU de Grenoble, Grenoble

40202

University of Louisville, Louisville

43210

Ohio State University Wexner Medical Center, Columbus

48109

University of Michigan, Ann Arbor

49546

Spectrum Health Medical Group, Grand Rapids

60007

Suburban Lung Associates, Elk Grove Village

60637

University of Chicago, Chicago

63110

Washington University, St Louis

77030

Houston Methodist Hospital, Houston

78626

St. Davids HealthCare, Georgetown

85258

HonorHealth, Phoenix

90502

Harbor UCLA, Torrance

95817

UC Davis, Sacramento

01805

Lahey Hospital & Medical Center, Burlington

Unknown

Krankenhaus Nord - Klinik Floridsdorf, Vienna

Hopital de la Cavale Blanche, Brest

Arnaud de Villeneuve Hospital, Montpellier

Hopital Pasteur, Nice

Bichat-Claude Bernard Hospital, Paris

CHU de Reims, Reims

CHU de Strasbourg, Strasbourg

Thorax Klinik Heidelberg, Heidelberg

UMC, Amsterdam

University Medical Center Groningen (UMCG), Groningen

Royal Brompton Harefield Trust, London

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Nuvaira, Inc.

INDUSTRY

NCT03639051 - Evaluation of the Safety and Efficacy of TLD in Patients with COPD | Biotech Hunter | Biotech Hunter